Ajax walloped Willem II 7-0, with Luis Suarez helping himself to a hat-trick, while Heerenveen were 1-0 winners against bottom side FC Volendam.
Dario Cvitanich got the balling rolling for Ajax in the second minute, with the striker netting again after Eyong Enoh had also got on the scoresheet.
A Suarez penalty and a strike from Urby Emanuelson made it 5-0 at the break, with Suarez completing his treble with two strikes after the interval.
Viktor Elm got the only goal of the game as Heerenveen were narrow winners against FC Volendam. Danijel Pranjic was sent off late on for the home side.
Elsewhere, Roy Makaay grabbed a hat-trick as Feyenoord defeated Heracles 5-1, while the exquisitely named Ricky van Wolfswinkel got a 61st-minute winner as Vitesse Arnhem defeated FC Groningen 3-2 to claim a valuable three points which lifts the visitors further clear of trouble at the bottom.