Middlesbrough will be without striker Jeremie Aliadiere and Willo Flood for the clash with Derby as both are injured.
Aliadiere is facing six weeks on the sidelines after suffering a broken toe in the defeat at Cardiff while Flood has a knee ligament injury.
The problem is likely to keep the former Celtic man out for the rest of the season.
Boro are also in the dark on the fitness of Emanuel Pogatetz as he continues to battle against a knee problem.
There is better news for defender Chris Riggott, who looks set for a substitute role after shaking off an hamstring strain.