Jason McAnulla will make his Allianz NFL debut for Tyrone against Galway at Pearse Stadium on Sunday.
McAnulla, who will line out at left-corner forward, is one of five changes Mickey Harte has made to the side that overcame Cork last weekend.
Johnny Curran loses out as John Devine has been named between the posts in what will be his first start of the season.
In the first line of defence there is also first 2010 appearance for Ciaran Gourley who takes over from Cathal McCarron at left corner-back.
Further up the field ther are two personnel switches in the half-forward line with Joe McMahon set to start on the right flank instead of Mark Donnelly while Colm McCullagh replaces his Dromore clubmate Eoin McCusker and will wear the number 11 jersey.
Tyrone (SF v Galway): J Devine; M Swift, Justin McMahon, C Gourley; D Harte, C Gormley, R McMenamin; A Cassidy, C Cavanagh; Joe McMahon, C McCullagh, R Mulgrew; T McGuigan, M Penrose, J McAnulla.