West Ham will be without Scott Parker against Arsenal but Carlton Cole is expected to return after being rested.
Parker is suffering from a leg injury and will be forced to miss the short trip to the Emirates Stadium but Cole is set for a recall after being rested against Chelsea last weekend.
Elsewhere, midfielder Mark Noble has recovered from an arm injury and could be pushing for a start in midfield but Kieron Dyer, Danny Gabbidon (both muscle) and Julian Faubert (hamstring) are out injured while Manuel Da Costa is suspended.
Meanwhile Zola knows the importance of the next seven days with crucial games also coming up against Everton, Liverpool and Manchester City.
"The next few days will be very important for us," Zola revealed. "We have massive games coming up. Tomorrow is a derby. It will be a difficult game and we will give our best because tomorrow's game will also be important for Tuesday and Saturday. It will be a massive week."